ANALYTICAL STANDARDIZATION OF GANDHAGARASAYANAM- ASIDDHA POLYHERBO MINERAL FORMULATION

Abstract

Gandhaga Rasayanam is a Siddhadrug widely used in the treatment of skin diseases. There are multiple methods and various herbo-mineral combinations abundantin Siddha texts to prepare Gandhaga rasayanam. The scientific standardization of traditional preparations is essential to ensure their quality, safety and efficacy. The present study aims to evaluate the physiochemical parameters of Gandhaga rasayanam prepared by, as per the reference Anuboga Vaidya Navaneedham- part 6. It was then subjected to physiochemical and phytochemical evaluation,tests for microbial load, aflatoxins and pesticide residuesas per AYUSH guidelines. The formulation exhibited the presence of characteristic bioactive ingredients in HPTLC profiling and phytochemical evaluation. The safety of this drug is assessed by screening microbial load, identification of aflatoxins and detection of pesticide levels. Thus, the study provides scientific evidence supporting the quality, efficacy, and standardization of the formulation highlighting its potential for further clinical and pharmacological investigations.