INFLUENCE OF POLYPHARMACY MANAGEMENT ON CARDIOVASCULAR OUTCOMES IN PTCA PATIENTS WITH LIFESTYLE AWARENESS: A PROSPECTIVE OBSERVATIONAL STUDY COMPARING PATIENTS WITH AND WITHOUT POLYPHARMACY INTERVENTIONS

Meena Kumari L; Sweety I; Bhaskar Muchahary; Lakshmikar A; Pravallika P

doi:10.47957/ijpda.v14i2.720

Authors

L Meena Kumari Department of Pharmacy Practice, Sri Venkateswara College of Pharmacy, Chittoor, Andhra Pradesh, India.
I Sweety Department of Pharmacy Practice, Sri Venkateswara College of Pharmacy, Chittoor, Andhra Pradesh, India.
Bhaskar Muchahary Department of Pharmacy Practice, Sri Venkateswara College of Pharmacy, Chittoor, Andhra Pradesh, India.
A.Lakshmikar Department of Pharmacy Practice, Sri Venkateswara College of Pharmacy, Chittoor, Andhra Pradesh, India.
P Pravallika Department of Pharmacy Practice, Sri Venkateswara College of Pharmacy, Chittoor, Andhra Pradesh, India.

DOI:

https://doi.org/10.47957/ijpda.v14i2.720

Keywords:

Polypharmacy management, PTCA, Coronary artery disease, Lifestyle modification, Medication adherence

Abstract

This prospective observational study evaluated the impact of polypharmacy management and lifestyle awareness on cardiovascular outcomes in patients undergoing percutaneous transluminal coronary angioplasty (PTCA). Conducted over six months in a secondary care hospital, 130 patients with coronary artery disease (CAD) were assessed using clinical data, medication records, and lifestyle modification scores. Interventions included medication review, optimization, dose adjustments, and patient counseling by clinical pharmacists, alongside lifestyle education. The majority of patients were males aged 51–60 years, with high prevalence of comorbidities such as hypertension and diabetes. Statins and dual antiplatelet therapy were the most frequently prescribed drugs. Patients receiving polypharmacy interventions demonstrated improved medication adherence, better awareness, and reduced rehospitalization rates compared to those without interventions. The findings highlight the critical role of structured pharmaceutical care and lifestyle modification in enhancing long-term cardiovascular outcomes and quality of life in post-PTCA patients, emphasizing the need for integrated, patient-centered management strategies.

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