Comprehensive review on various medicinal plants having potent anti-diabetic activity
Keywords:
Botanical name, extraction, anti-diabetic, mechanismAbstract
A review on medicinal plants possessing anti-diabetic activity. Brief description of parts used, extraction and mechanism of induction of diabetes is presented. Diabetes is a metabolic disorder characterised by disturbances in carbohydrate, protein and fat metabolism. Diabetes may be controlled by diet management, insulin injection and by oral hypoglycaemic agents. Herbal medicine have more significance due to their safety, efficacy, and easy availability.medicinal plants are popularly known for their health benefits.By suggestion of ethanobotanical information about 800 plants shows antidiabetic potential. The most common active constituents to treat diabetes is Flavonoids, tannnnins, phenolic acids, alkaloids. Various extarctions like aqueous, methanolic, ethanolic,dichloromethane, petroleum ether, and hexane were used to demonstrate effective hypoglycaemic activity. Various models like streptozotocin (STZ)-induced diabetes, Alloxan-induced diabetes, alloxan-monohydrate induced diabetes, streptozotocin+ nicotinamide induced diabetes mellitus in rats are used to induce diabetes.
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