A Concise Review on Microspheres for Targeted Drug Delivery
Keywords:
Targeted drug delivery system, Microspheres, Research updateAbstract
Most of the recent dosage forms have poor pharmacokinetic and biopharmaceutical properties. Hence there is need to develop a suitable delivery system that distributes the active drug molecule only to the site of action, without affecting other tissue or organs. Targeted drug delivery is a method of delivering drugs to the patients at the targeted site or the site of action. This improves efficacy of treatment by reducing side effects of the drug administered. The inherent advantages of this techniques lead to reduction in dose of drug as well as reduced side effects. Various drug carriers which can be used in this advanced delivery system are Lipoproteins, Liposomes, Microspheres. The present review deals with the targeted drug delivery system, its advantages, disadvantages, need of Targeted drug delivery system and research update on Targeted drug delivery system.
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References
Siepmann J, Siepmann F (2006) Microparticles used as drug delivery systems. Progr Colloid Polym Sci 133(2): 15-21.
Agrawal P, Rajput M (2010) Microspheres in cancer therapy. Ind J Cancer 47(4): 458-468.
Laurent A (2007) Microspheres and non-spherical particles for embolization. Tech Vasc Interventional Rad 10(4): 248-256.
Chao P, Deshmukh M, Kutscher H, Gao D, Rajan SS, et al. (2010) Pulmonary targeting microparticulate camptothecin delivery sys-tem: anti-cancer evaluation in a rat orthotopic lung cancer model. Anticancer Drugs 21(1): 65-76.
Fournier E, Passirani C, Colin N, Breton P, Sagodira S, et al. (2004) Development of novel 5-FU-loaded poly(methylidene malonate 2.1.2)-based microspheres for the treatment of brain cancers. Eur J Pharm Biopharm 57(2): 189-197.
VJ Mohanraj, Y Chen, Nanoparticles – A Review, Tropical Journal of Pharmaceutical Research 2006; 5(1):561-564.
A.R. Mullaicharam, Nanoparticles in Drug Delivery systems, International Journal of Nutrition, Pharmacology, Neurological dis-eases 2011; 1(2):103-108.
Elvis A. Martis, Rewa R. Badve, Mukta D. Degwekar, Nanotechnology Based Devices and Applications in Medicine: An Overview 2013; 3(1):69-70.
Prabhakar Vishvakrama and Saurabh Sharma, Liposomes: An Overview, Interna-tional Journal of Research in Pharmaceutical and Biomedical Sciences 2012; 3(3):1074-1076.
Kant Shashi, Kumar Satinder, Prashar Bharat, A Complete Review on Liposomes, International research Journal of Pharmacy 2012;3(7):10-15.
D.D. Lasic, Applications of Liposomes, Vol-ume 1, edited by R. Lipowsky and E. Sack-mann 493-494.
Prasanth v.v, Akash Chakraborthy Moy, Sam T Mathew, Rinku Mathapan, Microspheres - An Overview, International Journal of Research in Pharmaceutical and Biomedical Sciences 2011;2(2):332-337.
Shagufta Khan, Tripti Tiwari, Neha Rao, Amit Joshi, Bal Krishna Dubey, Microspheres: A Review, World Journal of Pharmacy and Pharmaceutical Sciences 2012; 1(1):126129,139-142.
Kataria Sahil1, Middha Akanksha1, Sandhu Premjeet1, Ajay Bilandi and Bhawana Ka-poor, Microsphere: A Review, International Journal of research in Pharmacy and Chemistry 2011; 1(4):1186-1188.
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