Isolation, Purification And Identification Of An An-timicrobial Compound From The Ethanol Seed Extract Of Syzygium cumini
Keywords:
Syzygium cumini; Antimicrobial; seed extract; Ethanol extraction; Candida albicansAbstract
This study focused on the isolation of a potential antimicrobial molecule from the seed of Syzygium cumini. The dry powdered seed were extracted with ethanol showed promising antimicrobial activity against the human pathogenic yeast, Candida albicans. The purification of this bioactive agent was done using RP-HPLC. The dried form of the active fraction was identified as 1-Monolinoleoylglycerol trimethylsilyl ether which was confirmed based on the results using FT-IR, 1H NMR, 13C NMR, GC and MS/MS analysis. From the overall observations, 1-Monolinoleoylglycerol trimethylsilyl ether is a promising bioactive molecule against the human pathogen Candida albicans which can be isolated at its purest form from the Syzygium cumini using the extract procedure identified in this present study.
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