A Review On Thiazole As Anticancer Agents

Authors

  • Harpreet Kaur Department of Pharmaceutical Chemistry, A.S.B.S.J.S.M. College of Pharmacy, Bela, 140111(Punjab), India
  • Anjali Goyal Department of Pharmaceutical Chemistry, A.S.B.S.J.S.M. College of Pharmacy, Bela, 140111(Punjab), India

Keywords:

Thiazole derivatives, Anticancer activity

Abstract

A study on heterocyclic compounds is of great interest in pharmaceutical area. This has catalyzed the discovery and development of much new heterocyclic chemistry and methods. In fact, one of the reasons for the wide spread use of heterocyclic compounds is that their structures can be suitably manipulated to achieve a required modification in function. Literature survey shows that the modifications of thiazole ring have highly effective to improve potency and lesser toxicity. The present review shows the important biological activity (Anticancer Activity) possesses by thiazole.

Downloads

Download data is not yet available.

References

Siddiqui N, Kumar SA, Ahsan W, Azad B. Diverse biological activity of thiazoles. IJDDR 2011;3:55-67.

Jagdale BS, Adole VA. Facile synthesis of 2-amino thiazole derivatives and their biological evaluation. Int. J. of Pharm. Research Scholars 2015;4:1-3.

Dondoni A, Merino P. Comprehensive Heterocyclic Chemistry ? 1996;3:467.

Shao J, Panek JS. Organic Letters 2004;6:3083.

Bhalla M, Hitkari A, Gujrati VR, Bhalla TN, Shankar K. Synthesis of new 1,2,4-triazolo 3,4,b1,3,4- thiadiazines and study of their ant candida and cytotoxic activity . Eur J Med Chem 1994;29:713.

Singh I, Kaur H, Kumar S, Lata S, Kumar A. Synthesis and antibacterial activity of 3-chloro 4- (substitutedphenyl) azetidinonyl/thiazolidinonyl-4- (3acetanilido) oxa/thiazoles. Int J PharmaSci and Res 2010;1:148-168.

Cai W, Liu A, Li Z, Dong W, Liu X, Sun N. Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives. ApplSci 2016;6:1-8.

Pucci JM, Bronson JJ. Antimicrobial Evaluation of Nocanthiacins, a Thiazole peptide class. Antimicrobial agents Chemotherapy 2004;48:3697-3701.

Siddiqui N, Arya SK, Ahsanb W, Azad B. Diverse biological activities of Thiazoles: A Retrospect. Int J of Drug Dev& Res 2011;3:156-164.

Chou TC, Zhang XG, Balog A, Su DU, Meng D, Savin K, Bertino JR, Danishefsky SJ. Proc Nat AcadSci USA 1998;95:9642-9647.

Chou TC, Zhang XG, Harris CR, Kuduk SD, Balog A, Savin K, Danishefsky SJ. Proc Nat AcadSci 1998;95:15798-15802.

Hofle G, Glaser N, Leibold T, Sefleow M. Pure ApplChem 1999;71:2019-2024.

Humphries TJ, Merritt GJ, Aliment GJ. PharmacolTher 1999;3:18–26.

Eicher T, Hauptmann S. The Chemistry of Heterocycles. Ch:5.29. 2005;149-154.

Kotadiya M. International Journal Of Advancement In Engineering Technology, Management and Applied Science (IJAETMAS) 2017;4:24-44.

Zagade AA, Senthilkumar GP. Der PharmaChemica 2011;3:523-537.

Lesyk R, Vladzimirska O, Holota S, Zaprutko L, Gzella A. Eur J Med Chem 2007;42:640-641.

Havrylyuk D, Zimenkovsky B, Vasylenko O, Zaprutko L, Gzella A, Lesyk R. Eur J Med Chem 2009;44:1396.

Kaminskyy D, Zimenkovsky B, Lesyk R. Eur J Med Chem 2009;44:3627.

Carter PH, Scherle PA, Muckelbauer JA, Voss ME, Liu RQ, Thompson LA, Tebben AJ, Solomon KA, Lo YC. ProcNatlAcadSci U.S.A 2001;98:11879.

Franchetti P, Grifantini M. Curr Med Chem 1999;6:599.

Matsuya Y, Kawaguchi T, Ishihara K, Ahmed K, Zhao QL, Kondo T, Nemoto H. Org. Lett 2006;8:4609.

Srivastava PC, Pickering MV, Allen LB, Streeter DG,Campbell MT, Witkowski JT, R.W. Sidwell, R.K. Robins. J. Med. Chem.1977;20:256.

Robins RK, Srivastava PC, Narayanan VL, Plowman L, Paull KD. J. Med. Chem.1982;25;107.

Weber G, Shen F, Orban TI, Kokeny S, Olah E. Adv. Enzyme Regul. 2003;43:47.

Tricot GJ, Jayaram HN, Heerema N, Weber G, Hoffman R. Cancer Res.1989;49:3696.

Merino P, Tejero T, Unzurrunzaga FJ, Franco S, Chiacchio U, Saita MG, Iannazzo D, Pipernoc A, Romeo G. Tetrahedron: Asym. 2005;16:3865.

Popsavin M, Spaic S, Svircev M, Kojic V, Bogdanovicb G, Popsavina V. Bioorg. Med. Chem. Lett. 2006;16:5317.

Popsavin M, Spaic S, Svircev M, Kojic V, Bogdanovicb G, Popsavina V. Bioorg. Med. Chem. Lett. 2007;17:4123.

Franchetti P, Cappellacci L, Pasqualini M, Petrelli R, Jayaprakasan V, Jayaram HN, Boyd DB, Jain MD, Grifantini M. Bioorg. Med. Chem. 2005;13:2045.

Wolff A, Technau A, Brandner G. Int. J. Oncol. 1997;11:123.

Ashkenazi S, Cleary TG. J. Med. Microbiol. 1990;32:255.

Sun XM , MacFarlane M, Zhuang J, Wolf BB, Green DR, Cohen GM. J. Biol. Chem. 1999;274:5053.

Bollag DM, McQueney PA, Zhu P, Hensens O, Koupal L, Liesch J, Goetz M, Lazaides E, Woods CM. Cancer Res.1995;55:2325.

Ahmed K, Matsuya Y, Nemoto H, Faisal S, Zaidi H, Sugiyama T, Yoshihisa Y, Shimizu T, Kondo T. Chem. Biol. Inter. 2009;177:218.

Grozav A, Porumb ID, Ga?ina LI, Filip L, Hanganu D. Cytotoxicity and Antioxidant Potential of Novel 2-(2-((1H-indol-5yl)methylene)-hydrazinyl)-thiazole Derivatives. Molecules. 2017:1-12.

Parrino B, Attanzio A, SpanoV,Cascioferro S, Montalbano A, Barraja P, Tesoriere L, Diana P,Cirrincione G, Carbone A. Synthesis, antitumor activity and CDK1 inhibiton of new thiazolenortopsentinanalogues. Eur J Med Chem. 2017:1-12.

Sadashiva R, Naral D, Kudva J, Madan SK, Byrappa K, Mohammed RS, Kumsi M. Synthesis, structure characterization, in vitro and in silicobiological evaluation of a new series of thiazole nucleus integrated with pyrazoline scaffolds. J Mole Stru. 2017:1-20.

Shaik SP, Vishnuvardhan MVPS, Sultana F, SubbaRao AV, Bagul C, Bhattacharjee D, Kapure JS, Jain N, Kamal A. Design and synthesis of 1,2,3-triazolo linked benzo[d]imidazo[2,1-b]thiazole conjugates as tubulin polymerization inhibitors. Bioorg& Med Chem 2017;25:3285–3297.

Zitouni GT, Alt?ntop MD, Ozdemir A, Kaplanc?kl? ZA, Çiftçi GA, Temel HE. Synthesis and Evaluation of Bis-thiazole Derivatives as New Anticancer Agents. Eur J Med Chem2015:1-16.

Yeap GY, Hrishikesan E, Chan YH, Mahmood WAK. Synthesis and salient chemosensing properties of a new thiazole-azo derivative. Tetrahedron 2017:1-11.

Hamed FI, Mohamed AA, Abouzied AS. The Uses of 2-Amino-4-Phenylthiazole in the Synthesis of Coumarin, Pyran, Pyridine and Thiazole Derivatives with Antitumor Activities. Open Acc Lib J 2017:1-16.

Santosa TA, Silvaa AC, Silvab EB, Gomesb PATM, Espindolab JWP, Cardosob MVO, Moreirac DRM, Leiteb ACL, Pereiraa VRA. Antitumor and immunomodulatory activities of thiosemicarbazones and 1,3-Thiazoles in Jurkat and HT-29 cells. Biomed Pharma 2016;82:555-560.

Mirza S, Naqvi SA, Khan KM, Salar U, Choudharya MI. Facile Synthesis of Novel Substituted Aryl-ThiazoleAnalogs via One-Pot Multicomponent Reaction as Potent Cytotoxic Agents against Cancer Cell lines. BioorgChem 2016:1-28.

Cai WX, Liu AL, Li ZM, Dong WL, Liu XH, Sun NB. Synthesis and Anticancer Activity of Novel Thiazole-5-Carboxamide Derivatives. Molecules. 2016:1-10.

Gomha SM, Salaheldin TA, Hassaneen HME, Aziz HMA, Khed MA. Synthesis, Characterization and Molecular Docking of Novel Bioactive Thiazolyl-Thiazole Derivatives as Promising Cytotoxic Antitumor Drug. Molecules 2015:1-17.

Ali AR, Bendary ER, Ghaly MA, Shehata IA. Synthesis, in vitro anticancer evaluation and in silico studies of novel imidazo[2,1-b]thiazole derivatives bearing pyrazole moieties. Eur J Med Chem. 2014;75:492-500.

Koppireddi S, Chilaka DRK, Avula S, Komsani JR , Kotamraju S, Yadla R. Synthesis and anticancer evaluation of 3-aryl-6-phenylimidazo [2,1-b]thiazoles. Bioorg& Med ChemLett. 2014;24:5428–5431.

Rostoma SAF, Faidallah HM, Radwan MF, Badr MH. Bifunctional ethyl 2-amino-4-methylthiazole-5-carboxylate derivatives, Synthesis and in vitro biological evaluation as antimicrobial and anticancer agents. EurJ Med Chem. 2014;76:170-181.

Zhang BL, Song LX, Li YF, Li YL, Guo YZ, Zhang E, Liu HM. Synthesis and biological evaluation of dehydroepiandrosterone-fusedthiazole, imidazo[2,1-b]thiazole, pyridine steroidal analogues. Steroids. 2014;80:92–101.

Saadi MSA, Faidallah HM, Rostom SAF. Synthesis and Biological Evaluation of Some 2,4,5-Trisubstituted Thiazole Derivatives as Potential Antimicrobial and Anticancer Agents, Arch.Pharm.Chem.Life Sci. 2008:424–434.

Dawood KM, Eldebss TMA, El-Zahabi HSA, Yousef MH, Metz P. Synthesis of some new pyrazole-based 1,3-thiazoles and 1,3,4-thiadiazoles as anticancer agents. Eur J Med Chem. 2013:1-23.

Published

2018-05-06
Statistics
350 Views | 1006 Downloads
Citatons

How to Cite

Harpreet Kaur, and Anjali Goyal. “A Review On Thiazole As Anticancer Agents”. International Journal of Pharmaceutics and Drug Analysis, vol. 6, no. 5, May 2018, pp. 509-22, https://ijpda.org/index.php/journal/article/view/397.

Issue

Section

Review Articles
Share |