Phytochemical and Acetyl cholinesterase activity in leaf extract of Ginkgo biloba L.
Keywords:
G. biloba leaf extract, serum, acetyl cholinesterase, flavonoidsAbstract
Alzheimer's disease (AD) is the most common cause of dementia in elderly humans. The plants have been chosen based on their use as memory enhancing as well as their nutrient value. These plants have been consumed as nutritious food and are believed to play an important role in health-promotion. The objectives of this study were to evaluate the phytochemical profiles in leaf extract of Gingko biloba and acetyl cholinesterase inhibitor in serum of 120mg/g treated with cognitive impairment of AD patients. Mini mental state examination (MMSE) shows the lower significant range in AD patients at P?0.01. Phytochemical test was observed in the methanol extract, which contained a progression of flavonoids and phenolics in triplicates assay by TLC. The results were expressed as IC50 and the percent of inhibition of acetylcholinesterase (AchE) activity.
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