Speciation of Binary Complexes of Cd(II) and Pb(II), With L-Glutamine In Cationic Micellar Medium
Keywords:
Chemical speciation, L-Glutamine, CTAB, Stability constants, MINIQUAD 75Abstract
A computer assisted pH-metric investigation has been made on the speciation of binary complexes of Cd(II) and Pb(II) with L-Glutamine(Gln). The titrations are carried out with sodium hydroxide in varying concentrations (0.0 – 2.5% w/v) of CTAB –water mixtures at an ionic strength of 0.16 mol L-1 and at a temperature of 303 K. The stability constants were determined using the computer program MINIQUAD 75. The best fit chemical models are chosen based on statistical parameters like crystallographic R-factor, ?2, skewness and kurtosis. The effect of solvent, dielectric constant of the medium and the electrostatic interactions between the complex species on the stability of the complexes are discussed.
Downloads
References
Teigen S, Andersen R, Programme on marine pollution (PMF), Trace metals in the marine environment. State of the Art and research needs. Croatian Society of Chemical Engineers, Zagreb, 1992; 124.
Di Toro, Allen M E, Bergman H L. Meyer J S, Paquin P R. Santore R C. Biotic ligand model of the acute toxicity of metals. Environ. Toxicol. Chem., 200; 2383-2396.
Felix H R. Keyser A. Schulin R. Proceedings of 5th International Conference on Biochemistry of trace elements. Vienna, Austria. 1997: 138.
Bergstrom J, Fürst P, Norée LO, Vinnars E. Intracellular free amino acid concentration in human muscle tissue. J Appl Physiol. 1974; 36(6): 693–697
Lacey JM. and Wilmore DW. Is glutamine a conditionally essential amino acid? Nutr. Rev. 1995; 48: 297 – 309.
Bartlett DL, Charland S, and Torosian MH. Effect of glutamine on tumor and host growth. Ann. Surg. Oncol., 1995; 2: 71 – 76.
Al-Saleh I.A.S. The biochemical and clinical consequences of lead poisoning. Med. Res. Rev. 1994; 14: 415-486.
Bressler, J. Kim, K. Chakraborti, T. and Goldstein, G. Molecular mechanisms of lead neurotoxicity. Neurochem. Res. 1999; 24: 595-600.
Bernard A. Renal dysfunction induced by cadmium: biomarkers of critical effects. BioMetals. 2004; 17: 519–523.
Nampoothiri LP. and Gupta S. Simultaneous effect of lead and cadmium on granulosa cells: A cellular model for ovarian toxicity. Reprod. Toxicol. 2006; 21: 179–185.
Rao RS and Rao GN. Computer Applications in Chemistry, Himalaya Publishing House, Mumbai, India. (2005).
Gran G. Determination of the equivalence point in potentiometric titrations. Part II. Analyst, 1952; 77: 661 – 671.
Gran G. Equivalence volumes in potentiometric titrations. Anal. Chim. Acta, 1988; 206: 111 – 123.
Rao GN. Complex equilibria of biological importance in aquo organic media-Computer augmented modeling studies, Ph.D. thesis, Andhra University, Visakhapatnam, India (1989).
Gans P, Sabatini A. and Vacca A. An improved computer program for the computation of formation constants from potentiometric data. Inorg. Chim. Acta, 1976; 18: 237-239.
Singh AK. and Manjula D. A fluorescence study of 1-paminophenyl-4-phenylbuta-1E, 3E-diene in organic solvents, 1,4-dioxane-water binary mixtures and micelles. J. Indian Chem. Soc., 2001; 78: 635-641.
Published
How to Cite
Issue
Section
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Copyright © Author(s) retain the copyright of this article.
