Intrinsic Medicinal Qualities and Current Status of Curcumin: An Incisive Review
Keywords:
Rosuvastatin calcium, Normal phase HPLC, Enantiomer, Impurities, Chiral methodAbstract
Curcumin is polyphenol product collected from the ground rhizomes of Curcuma Longa, which are commonly known as Turmeric. Curcumin has been procured by solevent extraction of turmeric and the purification of the extract by crystallization method. Traditionally turmeric is used as colouring agent in foods and textiles. Colouring principles are present to an intensity of 3-5 percent in turmeric and lesser amount of oils and resins, proteins, sugars may be naturally present in turmeric. Curcumin is an oily pigment and contains volatile oils like tumerone and zingiberone that are practically insoluble at neutral pH and in water at acidic medium. It is freely soluble in alkali. It is stable in acids and at high temperatures, but unstable in presence of light and in alkaline conditions. It has the poor bioavailability. To improve of bioavailability of curcumin various approaches have been over taken. Curcimin has widely used in ancient Indian medicine to ailment anorexia, diabetic wounds, billary disorders and rheumatism and therapeutically significant for its Antiseptic Activity, Cardiovascular Effects, Anticarcinogenic Effects, Hepatoprotective Effects etc. Recent study showed that curcumin has Anticancer Activity.
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