Influence of Anionic Micelles on Protonation Equilibria of L-Dopa and Catechol

T.V.S.P.V.SATYA GURU; V. RAVI KUMAR; G.NAGESWARA RAO

Influence of Anionic Micelles on Protonation Equilibria of L-Dopa and Catechol

Authors

T.V.S.P.V.SATYA GURU Department of Chemistry, Vignan’s Institute of Information Technology, Duvvada, Visakhapatnam, India
V. RAVI KUMAR Department of Chemistry, Vignan’s Institute of Information Technology, Duvvada, Visakhapatnam, India
G.NAGESWARA RAO Department of Inorganic and Analytical Chemistry, Andhra University Visakhapatnam-530 003, India

Keywords:

Protonation equilibria, MINIQUAD75, sodium lauryl sulphate, L-Dopa, Catechol

Abstract

The impact of sodium lauryl sulphate (SLS) on the protonation equilibria of L-Dopa and catechol has been studied in
various concentrations (0.0-2.5% w/v) of SLS solution maintaining an ionic strength of 0.16 mol L-1 at 303 K. The
protonation constants have been calculated with the computer program MINIQUAD75 and the best fit models have been
selected based on statistical parameters. The trend of log values of step-wise protonation constants with mole fraction of the
medium has been explained based on electrostatic and non-electrostatic forces operating on the protonation equilibria. The
effects of errors on the protonation constants have also been presented.

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Published

2014-11-06

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How to Cite

T.V.S.P.V.SATYA GURU, V. RAVI KUMAR, and G.NAGESWARA RAO. “Influence of Anionic Micelles on Protonation Equilibria of L-Dopa and Catechol”. International Journal of Pharmaceutics and Drug Analysis, vol. 2, no. 11, Nov. 2014, pp. 815-21, https://ijpda.org/index.php/journal/article/view/123.