FORMULATION AND EVALUATION OF DISPERSABLE TABLET OF CEFIXIME TRIHYDRATE

Sunil Kumar BG; Felix Joe.V; Vishwanath B.A

FORMULATION AND EVALUATION OF DISPERSABLE TABLET OF CEFIXIME TRIHYDRATE

Authors

Sunil Kumar BG Department of pharmaceutics, Aditya Bangalore Institute for Pharmacy Education & Research, Bangalore- 560064
Felix Joe.V Department of pharmaceutics, Aditya Bangalore Institute for Pharmacy Education & Research, Bangalore- 560064
Vishwanath B.A Department of pharmaceutics, Aditya Bangalore Institute for Pharmacy Education & Research, Bangalore- 560064.

Keywords:

Cefixime trihydrate, Dispersible tablet, Direct compression, co processed superdisintegrants, Release kinetics

Abstract

The objective of the study is to develop cefixime trihydrate orally dispersible tablet using co processed super disintegrants
and comparative study with the marketed product. Cefixime trihydrate orally dispersible tablet was prepared by direct
compression method using co processed super disintegrants such as cross povidone and sodium starch glycolate in different
concentrations. The developed oral disintegrating tablets were evaluated for different physical chemical evaluations like
drug content, hardness, friability, weight variation, wetting time, In vitro disintegration time, In-vitro drug release etc. All
formulations had shown the results within the prescribed limits.

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Published

2014-11-19

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How to Cite

Sunil Kumar BG, Felix Joe.V, and Vishwanath B.A. “FORMULATION AND EVALUATION OF DISPERSABLE TABLET OF CEFIXIME TRIHYDRATE”. International Journal of Pharmaceutics and Drug Analysis, vol. 2, no. 11, Nov. 2014, pp. 858-69, https://ijpda.org/index.php/journal/article/view/120.