EFFECT OF POORNA CHANDROTHAYA CHENDOORAM (METALLIC DRUG) ON LIVER DETOXIFICATIVE ENZYMES AND SERUM MET HEMOGLOBIN LEVELS IN YOUNG MALE RATS

P.Muthukumaran; Dr. V Hazeena Begum

EFFECT OF POORNA CHANDROTHAYA CHENDOORAM (METALLIC DRUG) ON LIVER DETOXIFICATIVE ENZYMES AND SERUM MET HEMOGLOBIN LEVELS IN YOUNG MALE RATS

Authors

P.Muthukumaran Department of Siddha Medicine Tamil University, Vakaiyur, Thanjavur 613 010, Tamilnadu, India.
Dr. V Hazeena Begum Department of Siddha Medicine Tamil University, Vakaiyur, Thanjavur 613 010, Tamilnadu, India

Keywords:

Cytochrome P-450, Met hemoglobin and Glutathione -S- transferase

Abstract

The effect of the Poorna Chandrothaya Chendooram was studied in male albino rats to explore its activities on liver. Poorna Chandrothaya Chendooram (3 mg/ml/100 gm) was given orally for seven weeks. The activity of Cytochrome P-450 and, were significantly decreased but the activity of glutathione -S- transferase were increased in the PCC administered rats rather than in control rats. Significant decrease in the activities of Cytochrome P-450 and Met hemoglobin and increase in the level of glutathione -S- transferase , indicate the defensive cytoprotective effects of Poorna Chandrothaya Chendooram.

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Published

2014-09-08

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How to Cite

P.Muthukumaran, and Dr. V Hazeena Begum. “EFFECT OF POORNA CHANDROTHAYA CHENDOORAM (METALLIC DRUG) ON LIVER DETOXIFICATIVE ENZYMES AND SERUM MET HEMOGLOBIN LEVELS IN YOUNG MALE RATS”. International Journal of Pharmaceutics and Drug Analysis, vol. 2, no. 9, Sept. 2014, pp. 700-4, https://ijpda.org/index.php/journal/article/view/108.