Menstrual cycle disorders: a correlation with genetic alterations


  • Shrishti Mishra RGS College of Pharmacy, Itaunja, Lucknow
  • Arti Verma RGS College of Pharmacy, Itaunja, Lucknow
  • Archita Tiwari Faculty of Pharmacy, Khwaja Moinuddin Chishti Language University, Lucknow
  • Bharat Mishra Institute of Pharmacy, Dr. Shakuntala Misra National Rehabilitation University, Lucknow



Menstrual irregularities, PCOS, obesity, Genetic alterations


The menstrual cycle is considered the fifth vital sign among women. The pituitary, thyroid, pancreas, adrenal, and ovaries are endocrine glands that play a crucial role in governing the menstrual cycle. Endocrine ailments trigger periods of menstruation disturbances throughout a woman's reproductive life. The duration and volume of menstrual bleeding can serve as indicators of endocrine problems. Oligomenorrhea, which refers to monthly periods longer than 35 days, is the most prevalent menstrual disruption observed in endocrine illnesses such as thyrotoxicosis, hypothyroidism, polycystic ovarian syndrome, Cushing's syndrome, and diabetes, based on the existing evidence. The intricate endocrine pathways are crucial in regulating a woman's menstrual cycle.. Menstrual Irregularities are caused due to eating disorders, extreme weight loss or too much exercising, Polycystic ovary syndrome (PCOS), Premature ovarian failure, Pelvic inflammatory disease (PID) and Pregnancy or breast-feeding. Mensesare affected by various factors like junk food, obesity, skipping breakfast lack of physical activity etc. PCOS, Diabetes, Hyperprolactinemia, Hypothyroidism, Thyrotoxicosis, and Cushing’s syndrome are some menstrual disorders which occur due to genetic alterations. All these disorders can be primarily treated by Nutritional Considerations and herbal treatments. In order to achieve a regular menstrual cycle and overcome these diseases, nutritional supplements and lifestyle modifications must be prioritized.


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How to Cite

Mishra, S., A. Verma, A. Tiwari, and B. Mishra. “Menstrual Cycle Disorders: A Correlation With Genetic Alterations”. International Journal of Pharmaceutics and Drug Analysis, vol. 12, no. 2, June 2024, pp. 38-47, doi:10.47957/ijpda.v12i2.596.



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