Phytochemistry, medicinal values and pharmacological potential of Datura stramonium L. review
Keywords:
Datura stramonium, medicinal, toxicology, phytochemistry, pharmacognosyAbstract
India has a great wealth of various naturally occurring plant drugs which have great potential pharmacological activities. Datura stramonium L.is a wild growing shrub belongs to the solanaceae family. It has both poisonous and medicinal properties. It is important medicinal plant from which tropane alkaloids, amino acids, tannin, phytic acids, carbohydrates have been isolated. Its diverse biological activities include anti-asthmatic, antibacterial, antifungal, anti-inflammatory, larvacidal, antispasmodic, antioxidant, antinociceptive, anti-rheumatoid and anti-ulcer activities. The neurotoxicity is attributed to the presence of tropane alkaloids which contain a methylated nitrogen atom (N-CH3) and include the anticholinergic drugs atropine, and scopolamine, as well as the narcotic cocaine. Traditionally it is used in skin disorder, ear pain, cough, fever and asthama. Its diverse biological activities include anti-asthmatic, antibacterial, antifungal, anti-inflammatory, larvacidal, antispasmodic, antioxidant, antinociceptive, anti-rheumatoid and anti-ulcer activities. Datura stramonium contain biologically active substances like alkaloids, atropine, scopolamine, tannin, carbohydrate and proteins. The present review is focused on the phytochemical, pharmacological studies, medicinal properties and toxicology of the Datura stramonium.
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